Label-free multiphoton microscopy reveals altered tissue architecture in hippocampal sclerosis

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Label-free microscopy: spectral imaging of multiphoton-excited cellular autofluorescence

A. Holloschi, HM. Kuhn, C. Müller, M. Worf, M. Rauen, T. Röder, W. Kessler, J. Mollenhauer and P. Kioschis 1 University of Applied Sciences Mannheim, Institute of Molecular and Cell Biology and Institute of Chemical Process Engineering, Mannheim, Germany 2 Steinbeis-Hochschule Berlin, Steinbeis-Insitut Multivariate Datenanalyse, Berlin, Germany 3 University of Southern Denmark, Lundbeckfonden C...

متن کامل

Label-Free Detection of Breast Masses Using Multiphoton Microscopy

Histopathology forms the gold standard for the diagnosis of breast cancer. Multiphoton microscopy (MPM) has been proposed to be a potentially powerful adjunct to current histopathological techniques. A label-free imaging based on two- photon excited fluorescence and second-harmonic generation is developed for differentiating normal breast tissues, benign, as well as breast cancer tissues. Human...

متن کامل

Label-free monitoring of colonic cancer progression using multiphoton microscopy

Real-time histology or virtual biopsy for the diagnosis of colonic cancer is of great medical significance. In this work, we show that label-free multiphoton imaging is feasible and effective in monitoring colonic cancer progression by providing cellular and subcellular details in fresh, unfixed, unstained colonic specimens. Our results also demonstrate the capability of using tissue quantitati...

متن کامل

Label-free photoacoustic microscopy of myocardial sheet architecture.

Cardiac myofibers are organized into sheet architectures, which contribute to up to 40% of the heart wall thickening for ejection of blood for circulation. It is important to delineate the sheet architecture for a better understanding of cardiac mechanisms. However, current sheet imaging technologies are limited by fixation-induced dehydration/deformation and low spatial resolution. Here we imp...

متن کامل

Label-free multiphoton microscopy of lipid droplets in oocytes, eggs and early embryos

The heating of microfluidic channels such as occurs in cell stretching and sorting devices was examined using the established technique of recording the intensity ratio between two fluorescent dyes, Rhodamine B (RhB) which is temperature sensitive and Rhodamine 110 (Rh110) which is not[1]. Microfluidic devices each consisting of a single channel and waveguide input were manufactured using ultra...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Epilepsia

سال: 2016

ISSN: 0013-9580

DOI: 10.1111/epi.13598